Confusion Over Black Pepper Extract

In a recentnewsletter , we spoke about the possible downsides to the use of concentrated black pepper extracts, namely BioPerine®, the most widely-used, trademarked product. Since this newsletter has been published we have had some confusion expressed about this subject and thus we would like to clarify matters. Essentially, the previous newsletter was referencing specifically the BioPerine® ingredient. The active ingredient in this extract is the alkaloid piperine, naturally occurring in black pepper. Here it is concentrated to 95%, which is exceedingly strong (concentrated), and this is where problems may arise.

It's a Matter of Degree

Piperine in an isolated form is available in other forms than the trademarked and concentrated BioPerine®. Lesser concentrations than the 95% piperine are used by many supplement manufacturers, and as those ingredients are not so strong, there is not the caution involved that the BioPerine® has. To put it in perspective, the amount of piperine in black pepper (Piper nigrum L.) varies from 2% to 7.4% and possibly as high as 9%.

To review, an incredibly concentrated 95% piperine will decrease intestinal impermeabilty and may also potentiate the action of pharmaceutical drugs. This means that the drugs will remain in the body longer, taking much more time to be metabolized and broken down by the liver.

Another Caution

Another issue which was not mentioned previously is its effects on reproduction in males and females. Highly concentrated piperine lowers sperm production and decreases testosterone in males, and may interfere in egg implantation in females. Again, this would occur only inrelatively long-term use of a highly concentrated piperine. Therefore, where fertility is an issue, caution may be advised before use.

Black pepper extracts in a lower concentration will increase bioavailabily of substances without the deleterious effects of BioPerine®. As mentioned, there are turmeric products available using black pepper (or ginger) as a synergist ingredient. On Evergreen's shelves, bothGaia Herbs andMyKind Herbals use a black pepper extractat a much lower concentration. There is a product for everyone, and we hope that with this knowledge customers may find the best option for them.